Leptin has a dramatic effect when we lose weight and levels of the hormone plummet. But this brings on hunger and increased food intake.
Essentially this hormone helps us maintain what our body believes is our normal weight, but that’s the problem.
For dieters, leptin can actually make it much harder to lose those extra inches.
We already know that people who are obese usually have very high levels of leptin.
This is because the brain doesn’t respond to leptin after a while, so these folks keep eating even though they have enough (or too much) fat already stored, a problem known as “leptin resistance.”
This causes fat cells to produce even more and more leptin that isn‘t able to communicate with the brain.
So, these leptin-resistant people keep eating and eating but always feel hungry.
This is similar to the way people with metabolic syndrome, pre-diabetes or type 2 diabetes have high levels of insulin and blood sugar.
These things keep building up because insulin isn’t able to act as the key that allows sugar to enter cells where it’s needed.